Memory T Cells Mediate Cardiac Allograft Vasculopathy and are Inactivated by Anti-OX40L Monoclonal Antibody
نویسندگان
چکیده
منابع مشابه
Donor CD4 T cells contribute to cardiac allograft vasculopathy by providing help for autoantibody production.
BACKGROUND The development of autoantibody after heart transplantation is increasingly associated with poor graft outcome, but what triggers its development and whether it has a direct causative role in graft rejection is not clear. Here, we study the development of antinuclear autoantibody in an established mouse model of heart allograft vasculopathy. METHODS AND RESULTS Humoral vascular cha...
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ژورنال
عنوان ژورنال: Cardiovascular Drugs and Therapy
سال: 2013
ISSN: 0920-3206,1573-7241
DOI: 10.1007/s10557-013-6502-9